Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11309079 | 0.96 | TSHR (0.53) | MAPK13MAPK12MAPK11MAPK14TSHR | |
| SCHEMBL11289947 | 0.81 | CYP3A4 (0.53) | MAPK13MAPK12MAPK11MAPK14TSHR | |
| SCHEMBL8977999 | 0.79 | NPC1 (0.46) | TSHRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL331059 | 0.78 | ALDH1A1 (0.59) | MAPK13MAPK12MAPK11MAPK14TSHR | |
| SCHEMBL4530935 | 0.78 | CYP3A4 (0.59) | MAPK13MAPK12MAPK11MAPK14TSHR | |
| SCHEMBL28976313 | 0.78 | GSK3B (0.51) | MAPK13MAPK12MAPK11MAPK14TSHR | |
| SCHEMBL11371987 | 0.77 | HPGD (0.54) | MAPK13MAPK12MAPK11MAPK14TSHR | |
| SCHEMBL8098491 | 0.77 | RAPGEF4 (0.59) | MAPK13MAPK12MAPK11MAPK14TSHR | |
| SCHEMBL4343605 | 0.75 | KMT2A (0.59) | CYP3A4ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4358566 | 0.75 | MEN1 (0.69) | TSHRMEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292736-A | Morpholinoalkylindenes as antiglaucoma agents | STERLING WINTHROP INC. (US) | 1994-03-08 | — | — | US | disclosed |