Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 10/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804752 | 0.80 | ALDH1A1 (0.39) | MCL1ALDH1A1MAPTLMNAGPR119 | |
| SCHEMBL7804783 | 0.79 | ALDH1A1 (0.38) | MCL1ALDH1A1MAPTLMNABCL2 | |
| SCHEMBL8112463 | 0.77 | ABCB1 (0.39) | MCL1ALDH1A1MAPTBCL2BCL2L1 | |
| SCHEMBL8107869 | 0.75 | ABCB1 (0.44) | MCL1ALDH1A1MAPTLMNABCL2 | |
| SCHEMBL9595803 | 0.75 | ABCB1 (0.44) | MCL1ALDH1A1MAPTLMNABCL2 | |
| SCHEMBL9596796 | 0.75 | ABCB1 (0.42) | MCL1ALDH1A1MAPTLMNABCL2 | |
| SCHEMBL8107606 | 0.75 | ABCB1 (0.42) | MCL1ALDH1A1MAPTLMNABCL2 | |
| SCHEMBL9399315 | 0.75 | ALDH1A1 (0.42) | MCL1ALDH1A1MAPTLMNABCL2 | |
| SCHEMBL9142600 | 0.75 | ABCB1 (0.48) | MCL1ALDH1A1MAPTLMNABCL2 | |
| SCHEMBL8107539 | 0.75 | TGM2 (0.37) | MCL1ALDH1A1MAPTBCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| WO-1993011128-A1 | AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |