Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804783 | 0.93 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNAGPR119HPGD | |
| SCHEMBL9399096 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAGPR119HPGD | |
| SCHEMBL9399315 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAGPR119HPGD | |
| SCHEMBL9020556 | 0.81 | CCR5 (0.43) | ALDH1A1MAPTLMNAGPR119HPGD | |
| SCHEMBL8098546 | 0.80 | MCL1 (0.36) | ALDH1A1MAPTLMNAGPR119HPGD | |
| SCHEMBL7805751 | 0.79 | SMN1; SMN2 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL7804672 | 0.78 | SMN1; SMN2 (0.40) | ALDH1A1MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL9520871 | 0.78 | CCR5 (0.36) | ALDH1A1MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL7809902 | 0.78 | PRMT5 (0.36) | GPR119HPGD | |
| SCHEMBL7806059 | 0.78 | PRMT5 (0.36) | GPR119HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773222-B1 | CARBAPENEM DERIVATIVE | EISAI CO LTD (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6037341-A | HAVING POTENT ANTIMICROBIAL EFFECTS OVER GRAM-POSITIVE BACTERIA AND GRAM-NEGATIVE BACTERIA | EISAI CO., LTD. (JP) | 2000-03-14 | — | — | US | disclosed |
| EP-0773222-A1 | NOVEL CARBAPENEM DERIVATIVE | Eisai Co., Ltd. (JP) | 1997-05-14 | — | — | EP | disclosed |