Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 6/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103590 | 0.92 | ALDH1A1 (0.38) | ALDH1A1BRD4CREBBPMAPTCYP1A2 | |
| SCHEMBL8097455 | 0.86 | ALDH1A1 (0.40) | POLBALDH1A1MAPTNPC1SMN1; SMN2 | |
| SCHEMBL8097587 | 0.84 | ALDH1A1 (0.39) | LMNAALDH1A1MAPTNPC1SMN1; SMN2 | |
| SCHEMBL8090064 | 0.83 | GUSB (0.43) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8099152 | 0.83 | ALDH1A1 (0.38) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL8097598 | 0.81 | ALDH1A1 (0.38) | LMNAALDH1A1MAPTCYP3A4CYP2C9 | |
| SCHEMBL8097385 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL8096918 | 0.81 | ALDH1A1 (0.38) | LMNAPOLBALDH1A1MAPTNPC1 | |
| SCHEMBL8098673 | 0.81 | ALDH1A1 (0.54) | POLBALDH1A1MAPTSMN1; SMN2CYP2C19 | |
| SCHEMBL8098463 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |