Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | LPL | P06858 | 2/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100545 | 1.00 | KCNH2 (0.54) | KCNH2PTGS2LPLLIPGSIGMAR1 | |
| SCHEMBL8095497 | 1.00 | KCNH2 (0.54) | KCNH2PTGS2LPLLIPGSIGMAR1 | |
| SCHEMBL8088663 | 0.98 | KCNH2 (0.51) | KCNH2PTGS2LPLLIPGSIGMAR1 | |
| SCHEMBL8096593 | 0.92 | CALM1 (0.50) | KCNH2SIGMAR1CNR1CNR2CALM1 | |
| SCHEMBL4077078 | 0.91 | LPL (0.56) | KCNH2LPLLIPGSIGMAR1 | |
| SCHEMBL27084220 | 0.90 | TDP1 (0.48) | KCNH2PTGS2LPLLIPGCNR1 | |
| SCHEMBL8095725 | 0.89 | LPL (0.54) | KCNH2LPLLIPGHTR2A | |
| SCHEMBL8093587 | 0.89 | LPL (0.54) | KCNH2LPLLIPGHTR2A | |
| SCHEMBL8096294 | 0.89 | LPL (0.54) | KCNH2LPLLIPGHTR2A | |
| SCHEMBL10106221 | 0.89 | LPL (0.54) | KCNH2LPLLIPGCALM1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |