Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088663 | 0.94 | KCNH2 (0.51) | CALM1KCNH2SIGMAR1L3MBTL1CNR1 | |
| SCHEMBL8095497 | 0.92 | KCNH2 (0.54) | CALM1KCNH2SIGMAR1L3MBTL1CNR1 | |
| SCHEMBL8098838 | 0.92 | KCNH2 (0.54) | CALM1KCNH2SIGMAR1L3MBTL1CNR1 | |
| SCHEMBL8100545 | 0.92 | KCNH2 (0.54) | CALM1KCNH2SIGMAR1L3MBTL1CNR1 | |
| SCHEMBL8099752 | 0.88 | MTNR1A (0.51) | CALM1MTNR1AMTNR1BOPRM1DRD3 | |
| SCHEMBL8086016 | 0.87 | CALM1 (0.55) | CALM1SIGMAR1MTNR1AMTNR1B | |
| SCHEMBL6547310 | 0.87 | CALM1 (0.55) | CALM1KCNH2SIGMAR1L3MBTL1HPGD | |
| SCHEMBL27084220 | 0.86 | TDP1 (0.48) | KCNH2L3MBTL1CNR1CNR2 | |
| SCHEMBL10106221 | 0.84 | LPL (0.54) | CALM1KCNH2L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL8094986 | 0.83 | LPL (0.49) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |