Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | PMM2 | O15305 | 1/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099439 | 0.85 | MEN1 (0.47) | MEN1KMT2AALDH1A1DRD2DRD3 | |
| SCHEMBL8090313 | 0.84 | MAPT (0.44) | MEN1KMT2AALDH1A1ALOX5PMM2 | |
| SCHEMBL8098928 | 0.81 | MAPT (0.44) | MEN1KMT2AMPIPHOSPHO1MAPT | |
| SCHEMBL8099171 | 0.80 | MEN1 (0.51) | MEN1KMT2AALDH1A1DRD2DRD3 | |
| SCHEMBL8099301 | 0.79 | DRD2 (0.46) | DRD2DRD3KCNH2MAPT | |
| SCHEMBL8787841 | 0.78 | CYP11B2 (0.40) | SIGMAR1KCNH2MAPT | |
| SCHEMBL8096492 | 0.78 | MAPT (0.64) | MEN1KMT2AALDH1A1ALOX5HTT | |
| SCHEMBL8098636 | 0.77 | MAPT (0.40) | MEN1KMT2AALDH1A1HTTMAPT | |
| SCHEMBL8098867 | 0.77 | MAPT (0.40) | ALDH1A1MAPTGAANPC1TP53 | |
| SCHEMBL432973 | 0.76 | ALOX5 (0.55) | MEN1KMT2AALDH1A1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634502-B | 3-Aryl substituted thiazolidine-4-ketone-2-methylene hydrazono methylene-1H-indole derivative and preparation method thereof | 复旦大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-114634502-A | 3-aryl substituted thiazolidine-4-ketone-2-ylidenehydrazonomethylene-1H-indole derivatives and preparation method thereof | 复旦大学 | 2022-06-17 | — | — | CN | disclosed |
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |
| US-4664694-A | NONPHYTOTOXIC | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0200415-A1 | Substituted thiazolidinones | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |