Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085451 | 0.95 | LTA4H (0.43) | DHFRDAOTAAR1LTA4HSAE1 | |
| SCHEMBL8096061 | 0.89 | LTA4H (0.46) | DAOTAAR1LTA4HIDO1SAE1 | |
| SCHEMBL8096568 | 0.87 | DAO (0.47) | DAOTAAR1IDO1MPOCNR1 | |
| SCHEMBL8099920 | 0.86 | TAAR1 (0.44) | DAOTAAR1LTA4HIDO1MPO | |
| SCHEMBL8099907 | 0.83 | CNR1 (0.44) | DAOTAAR1LTA4HIDO1MPO | |
| SCHEMBL8094436 | 0.83 | LMNA (0.50) | DHFRLTA4HTP53 | |
| SCHEMBL10916484 | 0.82 | DHFR (0.53) | DHFR | |
| SCHEMBL8095568 | 0.82 | CNR1 (0.49) | TAAR1LTA4HCNR1CNR2TP53 | |
| SCHEMBL8101996 | 0.82 | LTA4H (0.44) | TAAR1LTA4HCNR1CNR2TP53 | |
| SCHEMBL8093981 | 0.81 | TAAR1 (0.46) | DAOTAAR1LTA4HIDO1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |