Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090313 | 0.78 | MAPT (0.44) | ADRB1HIF1AXPO1MEN1KMT2A | |
| SCHEMBL14680395 | 0.74 | MEN1 (0.48) | ADRB1XPO1MEN1KMT2AAR | |
| SCHEMBL8105676 | 0.72 | ADRB1 (0.33) | ADRB1HIF1AXPO1HTR7AR | |
| SCHEMBL8098867 | 0.69 | MAPT (0.40) | — | |
| SCHEMBL8090530 | 0.68 | ADRB1 (0.39) | ADRB1XPO1MEN1KMT2A | |
| SCHEMBL18598250 | 0.68 | MEN1 (0.42) | ADRB1XPO1MEN1KMT2A | |
| SCHEMBL8105974 | 0.67 | MEN1 (0.49) | MEN1KMT2A | |
| SCHEMBL8787841 | 0.66 | CYP11B2 (0.40) | — | |
| SCHEMBL8099139 | 0.65 | MAPT (0.36) | HIF1AMEN1KMT2A | |
| SCHEMBL8098928 | 0.65 | MAPT (0.44) | GSK3AGSK3BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |