Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099494 | 1.00 | SIGMAR1 (0.50) | SIGMAR1HTR1ASLC6A4SLC6A3NAMPT | |
| SCHEMBL3894933 | 0.81 | SIGMAR1 (0.50) | SIGMAR1HTR1ASLC6A4SLC6A3PRCP | |
| SCHEMBL2032504 | 0.81 | SIGMAR1 (0.50) | SIGMAR1HTR1APRCPOPRM1MAOB | |
| SCHEMBL3894893 | 0.81 | SIGMAR1 (0.50) | SIGMAR1HTR1ASLC6A4SLC6A3PRCP | |
| Bromide SCHEMBL2033211 | 0.80 | SIGMAR1 (0.49) | SIGMAR1HTR1APRCPOPRM1MAOB | |
| SCHEMBL12472928 | 0.79 | SLC6A4 (0.47) | SLC6A4SLC6A3NAMPTMEN1ALDH1A1 | |
| SCHEMBL22916246 | 0.79 | SLC6A4 (0.47) | SLC6A4SLC6A3NAMPTMEN1ALDH1A1 | |
| SCHEMBL21916845 | 0.79 | SLC6A4 (0.47) | SLC6A4SLC6A3NAMPTMEN1ALDH1A1 | |
| SCHEMBL8437280 | 0.79 | SLC6A4 (0.47) | SLC6A4SLC6A3NAMPTMEN1ALDH1A1 | |
| SCHEMBL13256435 | 0.79 | SLC6A4 (0.47) | SLC6A4SLC6A3NAMPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763005-B1 | TETRAHYDROINDENO[1,2-d][1,3,2]OXAZABOROLES AND THEIR USE AS ENANTIOSELECTIVE CATALYSTS | SEPRACOR INC (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0763005-A4 | TETRAHYDROINDENO[1,2-d][1,3,2]OXAZABOROLES AND THEIR USE AS ENANTIOSELECTIVE CATALYSTS | SEPRACOR INC (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0763005-A1 | TETRAHYDROINDENO[1,2-d][1,3,2]OXAZABOROLES AND THEIR USE AS ENANTIOSELECTIVE CATALYSTS | SEPRACOR, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5495054-A | REDUCING PROCHIRAL KETONES TO ENANTIOMERICALLY PURE ALCOHOLS WITH BORANE REDUCING AGENT | SEPRACOR, INC. (US) | 1996-02-27 | — | — | US | disclosed |
| WO-1995032937-A1 | TETRAHYDROINDENO[1,2-d][1,3,2]OXAZABOROLES AND THEIR USE AS ENANTIOSELECTIVE CATALYSTS | SEPRACOR, INC. (US) | 1995-12-07 | — | — | WO | disclosed |