Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 6/20 | 0.46 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894933 | 1.00 | SIGMAR1 (0.50) | SIGMAR1HTR1APRCPMAOBMAOA | |
| SCHEMBL8099489 | 0.81 | SIGMAR1 (0.50) | SIGMAR1HTR1APRCPMAOBMAOA | |
| SCHEMBL2032504 | 0.81 | SIGMAR1 (0.50) | SIGMAR1HTR1APRCPMAOBMAOA | |
| SCHEMBL8099494 | 0.81 | SIGMAR1 (0.50) | SIGMAR1HTR1APRCPMAOBMAOA | |
| Bromide SCHEMBL2033211 | 0.80 | SIGMAR1 (0.49) | SIGMAR1HTR1APRCPMAOBMAOA | |
| SCHEMBL7538877 | 0.77 | SIGMAR1 (0.55) | SIGMAR1HTR1APRCPMAOBMAOA | |
| SCHEMBL9277494 | 0.71 | SIGMAR1 (0.41) | SIGMAR1HTR1APRCPMAOBMAOA | |
| SCHEMBL8395590 | 0.71 | SIGMAR1 (0.59) | SIGMAR1HTR1AMAOBMAOAGRIN2B | |
| SCHEMBL7485740 | 0.69 | SIGMAR1 (0.47) | SIGMAR1HTR1APRCPOPRM1CHRNB2 | |
| SCHEMBL1969755 | 0.68 | HTR1A (0.62) | SIGMAR1HTR1AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598420-B1 | Rasagiline formulations and processes for their preparation | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2009-10-06 | — | — | US | claimed |
| US-7619117-B1 | Rasagiline formulations and processes for their preparation | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2009-11-17 | — | — | US | disclosed |
| US-7598420-B1 | Rasagiline formulations and processes for their preparation | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2009-10-06 | — | — | US | disclosed |
| US-7572834-B1 | Rasagiline formulations and processes for their preparation | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2009-08-11 | — | — | US | disclosed |