Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | C5 | P01031 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481365 | 0.90 | PTGS1 (0.53) | CCR2PTGS2PTGS1PTGDRPTGDR2 | |
| SCHEMBL8092076 | 0.79 | PTGS1 (0.47) | CCR2PTGS2PTGS1PTGDRPTGDR2 | |
| SCHEMBL8104951 | 0.78 | HPGD (0.53) | PTGS2PTGS1FFAR1TTRCYP1A2 | |
| SCHEMBL15456906 | 0.78 | CHRM1 (0.48) | PTGS1 | |
| SCHEMBL8099718 | 0.76 | PTGS1 (0.68) | CCR2PTGS2PTGS1MEN1MAPT | |
| SCHEMBL7160901 | 0.76 | FFAR1 (0.60) | CCR2PTGS2PTGS1PTGDRPTGDR2 | |
| SCHEMBL8523577 | 0.76 | PTGS1 (0.58) | CCR2PTGS2PTGS1PTGDRPTGDR2 | |
| SCHEMBL7162523 | 0.75 | PTGS1 (0.59) | CCR2PTGS2PTGS1PTGDRPTGDR2 | |
| SCHEMBL8481368 | 0.73 | PTGS1 (0.52) | CCR2PTGS2PTGS1PTGDRPTGDR2 | |
| SCHEMBL9657574 | 0.73 | PTGS1 (0.60) | CCR2PTGS2PTGS1PTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848703-B1 | DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLO-OXYGENASE II | NYCOMED AUSTRIA GMBH (AT) | 2000-09-27 | — | — | EP | disclosed |