Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 4/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098993 | 0.85 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1RXRAHTT | |
| SCHEMBL8086250 | 0.84 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1ESR1ESR2ACHE | |
| SCHEMBL8098969 | 0.83 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1RXRA | |
| SCHEMBL8095670 | 0.82 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1ESR1ESR2ACHE | |
| SCHEMBL8099284 | 0.81 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1ESR1ESR2ACHE | |
| SCHEMBL8094415 | 0.80 | RXRA (0.31) | ALDH1A1L3MBTL1RXRA | |
| SCHEMBL8086371 | 0.80 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1ESR1ESR2LMNA | |
| SCHEMBL8100840 | 0.79 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1ESR1ESR2ACHE | |
| SCHEMBL8101932 | 0.79 | CYP19A1 (0.31) | — | |
| SCHEMBL8099461 | 0.78 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1ESR1ESR2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5807961-A | Polyamic acid, polyimide film and liquid crystal aligning film and liquid crystal display element using the formers | CHISSO CORPORATION (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |