Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1659994 | 0.84 | KDM4E (0.52) | RAB9ANPC1KDM4EADORA3ADORA2A | |
| SCHEMBL8108176 | 0.83 | KDM4E (0.56) | RAB9ANPC1CYP1A2KDM4EMAPT | |
| SCHEMBL8092386 | 0.82 | NPC1 (0.55) | RAB9ANPC1KDM4EADORA3ADORA2A | |
| SCHEMBL8105987 | 0.82 | NPC1 (0.55) | RAB9ANPC1KDM4EADORA3ADORA2A | |
| SCHEMBL8108255 | 0.81 | KDM4E (0.65) | RAB9ANPC1KDM4EADORA2AHSD17B10 | |
| SCHEMBL8099857 | 0.80 | NR1H4 (0.50) | RAB9ANPC1CYP1A2KDM4EHSD17B10 | |
| SCHEMBL8106156 | 0.80 | PKM (0.45) | RAB9ANPC1CYP1A2KDM4EHPGD | |
| SCHEMBL1834856 | 0.80 | ADORA3 (0.47) | NPC1KDM4EADORA3ADORA2AADORA2B | |
| SCHEMBL8100175 | 0.79 | GRM5 (0.55) | RAB9ANPC1KDM4EADORA3ADORA2A | |
| SCHEMBL8105559 | 0.79 | RAB9A (0.54) | RAB9ANPC1KDM4EADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071930-A | FOR INHIBITION OF MITOSIS OR TUMOR GROWTH | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-06-06 | — | — | US | disclosed |