SCHEMBL809993

SCHEMBL809993

COC(=O)COc1ccc(OC(C)C(=O)OC)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.50
L3MBTL1 Q9Y468 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
POLB P06746 1/20 0.48
MAPT P10636 3/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.46
ALDH2 P05091 1/20 0.44
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4262686 0.85 KMT2A (0.48) L3MBTL1MEN1KMT2APOLBMAPT
SCHEMBL5046734 0.84 MAPT (0.45) L3MBTL1MEN1KMT2AMAPTALDH1A1
SCHEMBL4250581 0.84 KMT2A (0.58) L3MBTL1MEN1KMT2APOLBMAPT
SCHEMBL4267095 0.83 MAPT (0.54) PTGS2L3MBTL1MEN1KMT2APOLB
SCHEMBL2116437 0.82 PTGS2 (0.66) PTGS2L3MBTL1MEN1KMT2APOLB
SCHEMBL4264041 0.81 PTGS2 (0.48) PTGS2L3MBTL1MEN1KMT2APOLB
SCHEMBL810052 0.81 HDAC1 (0.45) GAAALDH2
SCHEMBL4268398 0.81 CYP4F2 (0.51) L3MBTL1MEN1KMT2APOLBMAPT
SCHEMBL9856571 0.81 ALDH1A1 (0.50) PTGS2L3MBTL1MEN1KMT2APOLB
SCHEMBL5046746 0.80 RECQL (0.48) L3MBTL1POLBMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902319-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-03-08 US disclosed
US-7902319-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-03-08 US disclosed
US-7902319-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-03-08 US disclosed
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-05-06 US disclosed
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-05-06 US disclosed
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-05-06 US disclosed
US-7671168-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-03-02 US disclosed
US-7671168-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-03-02 US disclosed
US-7671168-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-03-02 US disclosed
US-20070141113-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-21 US disclosed
US-20070141113-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-21 US disclosed
US-20070141113-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM DDT, ACMSD, HPD PTGS2 2456/4885L3MBTL1 4852/4885MEN1 4250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.