Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100023 | 0.82 | LTA4H (0.36) | TSHRSMN1; SMN2CYP2C19LMNABLM | |
| SCHEMBL8097672 | 0.80 | LTA4H (0.35) | TSHRSMN1; SMN2 | |
| SCHEMBL8097239 | 0.78 | LTA4H (0.34) | — | |
| SCHEMBL8780860 | 0.77 | TDP1 (0.43) | TSHRCYP3A4KDM4EALDH1A1GAA | |
| SCHEMBL9187620 | 0.73 | TDP1 (0.39) | TSHRSMN1; SMN2CYP3A4ALDH1A1MAPT | |
| SCHEMBL8934009 | 0.71 | TSHR (0.38) | TSHRSMN1; SMN2PTGS1CYP2C9CYP2C19 | |
| SCHEMBL7067524 | 0.71 | HTT (0.41) | TSHRSMN1; SMN2CYP2C19CYP3A4KDM4E | |
| SCHEMBL5009085 | 0.70 | ALDH1A1 (0.37) | TSHRKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8652282 | 0.70 | KCNH2 (0.41) | TSHRCYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL5003760 | 0.70 | KCNH2 (0.41) | TSHRCYP3A4KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103867-A | METAL COMPLEX MIXED WITH LEWIS AND/OR PROTIC ACIDS; SIMPLIFICATION, EFFICIENCY, HALOGEN-FREE STARTING MATERIALS | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | disclosed |