Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2799552 | 0.78 | POLB (0.37) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL21823799 | 0.76 | KDM4E (0.43) | KDM4EPTGS1BACE1POLBMEN1 | |
| SCHEMBL4889898 | 0.75 | ALDH1A1 (0.46) | KDM4EALDH1A1BACE1RAB9AATM | |
| SCHEMBL14390458 | 0.74 | ALDH1A1 (0.33) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL28230730 | 0.73 | ADRA2A (0.42) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL31365812 | 0.72 | ADRA2A (0.40) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL6785112 | 0.72 | MEN1 (0.44) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL8109502 | 0.72 | ADRA2A (0.40) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL28095379 | 0.71 | CES2 (0.49) | KDM4EALDH1A1SLC6A9MEN1KMT2A | |
| SCHEMBL5552843 | 0.71 | LMNA (0.34) | KDM4EALDH1A1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524018-B1 | Isoxazole herbicides | RHONE POULENC AGRICULTURE (GB) | 2000-10-18 | — | — | EP | disclosed |
| US-5424276-A | Herbicidal 4-acyl-5-pyridylisoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-06-13 | — | — | US | disclosed |
| US-5366957-A | Plant growth regulators | RHONE-POULENC ARGRICULTURE LTD (GB) | 1994-11-22 | — | — | US | disclosed |
| EP-0524018-A1 | Isoxazole herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-01-20 | — | — | EP | disclosed |