Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 3/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | GRK5 | P34947 | 2/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7867606 | 0.98 | LIMK1 (0.40) | LIMK1DYRK1BCHEK1GRK5CSNK1A1 | |
| SCHEMBL10646511 | 0.70 | ALDH1A1 (0.43) | LIMK1DYRK1BCHEK1GRK5CSNK1A1 | |
| SCHEMBL31649988 | 0.69 | ADORA3 (0.38) | NR4A1NR4A2 | |
| SCHEMBL29756180 | 0.68 | SMN1; SMN2 (0.42) | LIMK1DYRK1BCHEK1GRK5CSNK1A1 | |
| SCHEMBL8100833 | 0.67 | RAB9A (0.33) | RAB9AKMT2AALDH1A1 | |
| SCHEMBL3582788 | 0.67 | NUDT1 (0.39) | DYRK1BCHEK1LRRK2CLK4LTK | |
| SCHEMBL8099491 | 0.66 | — | — | |
| SCHEMBL8106672 | 0.66 | — | — | |
| Bromide SCHEMBL4063563 | 0.66 | RAB9A (0.32) | RAB9AKMT2A | |
| SCHEMBL4059934 | 0.66 | CHEK1 (0.35) | LIMK1DYRK1BCHEK1GRK5CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130335-A | N-([1,2,4]triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2000-10-10 | — | — | US | disclosed |
| US-6005108-A | POST-EMERGENCE TOTAL VEGETATION CONTROL OR SELECTIVE CONTROL OF WEEDS IN WHEAT, RICE AND OIL-SEED RAPE CROPS | JOHNSON TIMOTHY C (US) | 1999-12-21 | — | — | US | disclosed |
| US-5965490-A | NOVEL COMPOUNDS WITH IMPROVED SELECTIVITY TO VALUABLE CROPS AND IMPROVED TOXICOLOGICAL AND ENVIRONMENTAL ATTRIBUTES; APPLYING TO CONTROL WEEDS BY EITHER PREEMERGENCE OR POSTEMERGENCE APPLICATION | DOW AGROSCIENCES LLC (US) | 1999-10-12 | — | — | US | disclosed |