Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101283 | 0.78 | KDM4E (0.45) | CYP2C9GAAATML3MBTL1ALDH1A1 | |
| SCHEMBL8100448 | 0.74 | CYP2C9 (0.38) | CYP2C9GAAATML3MBTL1ALDH1A1 | |
| SCHEMBL9280347 | 0.73 | PTGDR2 (0.51) | CYP2C9ATML3MBTL1ALDH1A1KDM4E | |
| SCHEMBL31697574 | 0.72 | TYMS (0.42) | CYP2C9GAAATML3MBTL1ALDH1A1 | |
| SCHEMBL3261982 | 0.72 | LMNA (0.45) | CYP2C9GAAATML3MBTL1ALDH1A1 | |
| SCHEMBL6074814 | 0.72 | CYP2C9 (0.46) | CYP2C9GAAATML3MBTL1ALDH1A1 | |
| SCHEMBL27491720 | 0.69 | GAA (0.50) | CYP2C9GAAATML3MBTL1ALDH1A1 | |
| SCHEMBL27766057 | 0.69 | GAA (0.56) | GAAL3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL25724165 | 0.68 | GAA (0.45) | CYP2C9GAAATMALDH1A1MAOA | |
| SCHEMBL11012886 | 0.68 | KMT2A (0.47) | GAAALDH1A1KDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591102-B1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA SC HOLDING AG (CH) | 2000-10-18 | — | — | EP | disclosed |
| US-5428162-A | For protecting organic materials against thermal, oxidative or light-induced degradation | CIBA-GEIGY CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0591102-A1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA-GEIGY AG (CH) | 1994-04-06 | — | — | EP | disclosed |