SCHEMBL3261982

SCHEMBL3261982

CCCCCOc1ccccc1C1C(=O)Oc2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.45
KMT2A Q03164 3/20 0.45
MAPT P10636 3/20 0.45
HTR2B P41595 2/20 0.45
MEN1 O00255 2/20 0.45
CYP3A4 P08684 2/20 0.45
NR1I2 O75469 1/20 0.45
CHRM2 P08172 1/20 0.45
ADRA2A P08913 1/20 0.45
OPRK1 P41145 1/20 0.45
SLC6A3 Q01959 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
TP53 P04637 5/20 0.44
GAA P10253 3/20 0.44
TSHR P16473 3/20 0.44
HTT P42858 1/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
GLA P06280 2/20 0.44
HPGD P15428 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8100448 0.83 CYP2C9 (0.38) HTR2BTP53GAATSHRHTT
SCHEMBL3261989 0.82 LMNA (0.46) LMNAKMT2AMEN1TP53GAA
Nonane SCHEMBL27663344 0.77 GAA (0.56) KMT2AMAPTMEN1GAACYP2C9
SCHEMBL9280347 0.77 PTGDR2 (0.51) KMT2AMEN1KDM4EALDH1A1GLA
SCHEMBL3896295 0.77 CYSLTR2 (0.47) KMT2AMAPTMEN1TSHRNPSR1
SCHEMBL28597652 0.74 KMT2A (0.47) KMT2AMAPTMEN1TSHRNPSR1
SCHEMBL28596989 0.74 KMT2A (0.47) KMT2AMAPTMEN1TSHRNPSR1
SCHEMBL28596988 0.74 KMT2A (0.47) KMT2AMAPTMEN1TSHRNPSR1
SCHEMBL8101283 0.73 KDM4E (0.45) LMNAKMT2AMAPTMEN1GAA
SCHEMBL8100443 0.72 CYP2C9 (0.38) LMNAMAPTCYP3A4NR1I2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3519489-A1 LOW EMISSIONS SCORCH INHIBITOR FOR POLYURETHANE FOAM Vanderbilt Chemicals, LLC (US) 2019-08-07 EP claimed
US-20180094120-A1 LOW EMISSIONS SCORCH INHIBITOR FOR POLYURETHANE FOAM VANDERBILT CHEMICALS, LLC 2018-04-05 US claimed
WO-2018064521-A1 LOW EMISSIONS SCORCH INHIBITOR FOR POLYURETHANE FOAM VANDERBILT CHEMICALS, LLC (US) 2018-04-05 WO claimed
US-10421851-B2 Low emissions scorch inhibitor for polyurethane foam VANDERBILT CHEMICALS, LLC 2019-09-24 US disclosed
EP-3519489-A1 LOW EMISSIONS SCORCH INHIBITOR FOR POLYURETHANE FOAM Vanderbilt Chemicals, LLC (US) 2019-08-07 EP disclosed
US-20180094120-A1 LOW EMISSIONS SCORCH INHIBITOR FOR POLYURETHANE FOAM VANDERBILT CHEMICALS, LLC 2018-04-05 US disclosed
WO-2018064521-A1 LOW EMISSIONS SCORCH INHIBITOR FOR POLYURETHANE FOAM VANDERBILT CHEMICALS, LLC (US) 2018-04-05 WO disclosed
US-8653284-B2 Lactone stabilizing compositions MILLIKEN & COMPANY (US) 2014-02-18 US disclosed
US-20100010124-A1 LACTONE STABILIZING COMPOSITIONS XIA JUSONG 2010-01-14 US disclosed
US-7601853-B2 Lactone stabilizing compositions MILLIKEN & COMPANY (US) 2009-10-13 US disclosed
EP-1824921-B1 LACTONE STABILIZING COMPOSITIONS MILLIKEN & CO (US) 2009-02-25 EP disclosed
US-20080217585-A1 LACTONE STABILIZING COMPOSITIONS XIA JUSONG 2008-09-11 US disclosed
US-7390912-B2 Lactone stabilizing compositions MILLIKEN & COMPANY (US) 2008-06-24 US disclosed
EP-1824921-A1 LACTONE STABILIZING COMPOSITIONS Milliken&Company (US) 2007-08-29 EP disclosed
US-20060135792-A1 Lactone stabilizing compositions MILLIKEN & COMPANY 2006-06-22 US disclosed
WO-2006065829-A1 LACTONE STABILIZING COMPOSITIONS MILLIKEN & COMPANY (US) 2006-06-22 WO disclosed
US-5488117-A FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1996-01-30 US disclosed
US-5488117-A FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1996-01-30 US disclosed
US-5369159-A Heat, oxidation and radiation resistance for polymers CIBA-GEIGY CORPORATION (US) 1994-11-29 US disclosed
US-5369159-A Heat, oxidation and radiation resistance for polymers CIBA-GEIGY CORPORATION (US) 1994-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080217585-A1 LACTONE STABILIZING COMPOSITIONS GLO1, LPO, CBR3 LMNA 411/4885KMT2A 2642/4885MAPT 3296/4885
US-20060135792-A1 Lactone stabilizing compositions GLO1, LPO, CBR3 LMNA 411/4885KMT2A 2642/4885MAPT 3296/4885
US-20100010124-A1 LACTONE STABILIZING COMPOSITIONS GLO1, LPO, CBR3 LMNA 411/4885KMT2A 2642/4885MAPT 3296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.