Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261982 | 0.83 | LMNA (0.45) | CYP2C9ATMTP53HTTGAA | |
| SCHEMBL9280347 | 0.82 | PTGDR2 (0.51) | CYP2C9ATMMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30561156 | 0.81 | ALDH1A1 (0.44) | CYP2C9ATMHTTGAAMAPK1 | |
| SCHEMBL5605404 | 0.81 | ALDH1A1 (0.44) | CYP2C9ATMHTTGAAMAPK1 | |
| SCHEMBL4604946 | 0.77 | GAA (0.41) | TP53HTTGAAMAPK1RAB9A | |
| SCHEMBL8101283 | 0.75 | KDM4E (0.45) | CYP2C9ATMGAATSHRALDH1A1 | |
| SCHEMBL8100443 | 0.74 | CYP2C9 (0.38) | CYP2C9ATMGAATSHRSMN1; SMN2 | |
| SCHEMBL28896928 | 0.73 | TP53 (0.50) | TP53HTTMAPK1RAB9AIDO1 | |
| SCHEMBL31697574 | 0.72 | TYMS (0.42) | CYP2C9ATMGAAALDH1A1KDM4E | |
| SCHEMBL6074814 | 0.72 | CYP2C9 (0.46) | CYP2C9ATMGAATSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591102-B1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA SC HOLDING AG (CH) | 2000-10-18 | — | — | EP | disclosed |
| CN-1040208-C | 3-(2-acyloxyethoxyphenyl) benzofuran-2-ones for use as stabilizers | SPECIALTY CHEMICALS HOLDING IN (CH) | 1998-10-14 | — | — | CN | disclosed |
| US-5428162-A | For protecting organic materials against thermal, oxidative or light-induced degradation | CIBA-GEIGY CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0591102-A1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA-GEIGY AG (CH) | 1994-04-06 | — | — | EP | disclosed |