Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100448 | 0.82 | CYP2C9 (0.38) | L3MBTL1SMN1; SMN2GLAALDH1A1MAPK1 | |
| SCHEMBL9280351 | 0.81 | ALOX15 (0.49) | SMN1; SMN2ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL8101283 | 0.77 | KDM4E (0.45) | L3MBTL1ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL3261982 | 0.77 | LMNA (0.45) | POLBL3MBTL1SMN1; SMN2GLAALDH1A1 | |
| SCHEMBL31697574 | 0.74 | TYMS (0.42) | POLBL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL8100443 | 0.73 | CYP2C9 (0.38) | L3MBTL1SMN1; SMN2ALDH1A1CYP2C9KDM4E | |
| SCHEMBL10228844 | 0.72 | PTGDR2 (0.55) | PTGDR2POLBL3MBTL1SMN1; SMN2GLA | |
| SCHEMBL340762 | 0.71 | L3MBTL1 (0.80) | PTGDR2POLBL3MBTL1SMN1; SMN2GLA | |
| SCHEMBL29682135 | 0.71 | L3MBTL1 (0.80) | PTGDR2POLBL3MBTL1SMN1; SMN2GLA | |
| SCHEMBL6074814 | 0.71 | CYP2C9 (0.46) | POLBL3MBTL1SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422415-A | Benzofuran derivative, phenolic antioxidant, secondary amine antioxidant; foams | CIBA-GEIGY CORPORATION (US) | 1995-06-06 | — | — | US | disclosed |
| US-5356966-A | Stabilizing organic material against oxidative, thermal or light iinduced degradation | CIBA-GEIGY CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| US-5356966-A | Stabilizing organic material against oxidative, thermal or light iinduced degradation | CIBA-GEIGY CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| US-5308899-A | Benzofuranone derivative, phenolic and secondary amine antioxidants | CIBA-GEIGY CORPORATION (US) | 1994-05-03 | — | — | US | disclosed |
| EP-0543778-A1 | Compositions protected against oxydation and scorching, respectively polyetherpolyol and polyurethane | CIBA-GEIGY AG (CH) | 1993-05-26 | — | — | EP | disclosed |