SCHEMBL810046

SCHEMBL810046

C=Cc1ccc(CCl)c2cc3c(OC(C)=O)cccc3cc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.35
LMNA P02545 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
ALOX12 P18054 1/20 0.35
NCOA1 Q15788 1/20 0.35
NCOA3 Q9Y6Q9 1/20 0.35
KMT2A Q03164 6/20 0.35
KDM4E B2RXH2 3/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
POLB P06746 2/20 0.35
GAA P10253 1/20 0.35
APEX1 P27695 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
PDE10A Q9Y233 2/20 0.35
MEN1 O00255 5/20 0.34
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809953 0.84 KDM4E (0.38) KDM4EL3MBTL1ALDH1A1TDP1PDE10A
SCHEMBL3619460 0.83 KMT2A (0.43) MAPTKMT2AKDM4EL3MBTL1ALDH1A1
SCHEMBL3627097 0.80 KMT2A (0.41) MAPTKMT2AKDM4EL3MBTL1ALDH1A1
SCHEMBL810291 0.78 CYP1A2 (0.40) L3MBTL1ALDH1A1HPGD
SCHEMBL809371 0.77 LMNA (0.40) MAPTLMNASMN1; SMN2ALOX12NCOA1
SCHEMBL809771 0.76 ALDH1A1 (0.36) KMT2AL3MBTL1ALDH1A1
SCHEMBL810223 0.75 L3MBTL1 (0.30) L3MBTL1
SCHEMBL809665 0.74 KMT2A (0.36) MAPTLMNASMN1; SMN2ALOX12NCOA1
SCHEMBL3628673 0.72 HTT (0.44) LMNASMN1; SMN2KMT2AKDM4EALDH1A1
SCHEMBL8613589 0.71 PTGS2 (0.41) MAPTLMNASMN1; SMN2ALOX12NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012015977-A3 HIGHLY PORTABLE AND STABLE WORK STATION HERSCHLER MATTHEW B (US) 2012-05-10 WO disclosed
EP-2192645-B1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORP (JP) 2011-11-30 EP disclosed
US-20110250525-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORPORATION (JP) 2011-10-13 US disclosed
EP-2192645-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME Tokuyama Corporation (JP) 2010-06-02 EP disclosed