Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102167 | 0.91 | DHODH (0.51) | DHODHCYP1A2CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL8102117 | 0.85 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8100896 | 0.85 | KMT2A (0.39) | DHODHCYP1A2CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL8102608 | 0.84 | PTPN1 (0.46) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8092785 | 0.83 | PTPN1 (0.48) | MAPTALDH1A1LMNAHTTTDP1 | |
| SCHEMBL8100744 | 0.82 | MAPT (0.51) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8092901 | 0.82 | ALDH1A1 (0.45) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8092964 | 0.80 | MAPT (0.46) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8102043 | 0.79 | HSP90AA1 (0.52) | DHODHMAPTALDH1A1LMNAKMT2A | |
| SCHEMBL8106476 | 0.79 | FGFR1 (0.46) | MAPTALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013674-A | INDENONE AMIDE DERIVATIVES, USEFUL FOR FOR THE INHIBITION OF LEUKOCYTE ADHERENCE TO ENDOTHELIAL CELLS; USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES, AS ARTHRITIS, ASTHAMA, PSORIASIS, RESPIRATORY DISTRESS SYNDROME, STROKE AND ULCER | ELI LILLY AND COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0882706-A1 | Cell adhesion inhibitors | ELI LILLY AND COMPANY (US) | 1998-12-09 | — | — | EP | disclosed |