Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102608 | 0.99 | PTPN1 (0.46) | PTPN1NR1H2NR1H3SOAT1ALDH1A1 | |
| SCHEMBL8102117 | 0.94 | ALDH1A1 (0.40) | PTPN1SOAT1ALDH1A1APAF1MITF | |
| SCHEMBL8092901 | 0.88 | ALDH1A1 (0.45) | PTPN1ALDH1A1APAF1MITFNPC1 | |
| SCHEMBL8092964 | 0.86 | MAPT (0.46) | PTPN1ALDH1A1APAF1MITFNPC1 | |
| SCHEMBL8100473 | 0.83 | DHODH (0.42) | ALDH1A1APAF1MITFNPC1RAB9A | |
| SCHEMBL8100744 | 0.82 | MAPT (0.51) | ALDH1A1APAF1MITFNPC1GAA | |
| SCHEMBL8106476 | 0.82 | FGFR1 (0.46) | ALDH1A1APAF1MITFNPC1GAA | |
| SCHEMBL8102167 | 0.79 | DHODH (0.51) | ALDH1A1APAF1MITFNPC1GAA | |
| SCHEMBL8092958 | 0.79 | HSP90AA1 (0.52) | PTPN1ALDH1A1NPC1GAARAB9A | |
| SCHEMBL8100694 | 0.78 | RAB9A (0.52) | PTPN1SOAT1ALDH1A1APAF1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013674-A | INDENONE AMIDE DERIVATIVES, USEFUL FOR FOR THE INHIBITION OF LEUKOCYTE ADHERENCE TO ENDOTHELIAL CELLS; USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES, AS ARTHRITIS, ASTHAMA, PSORIASIS, RESPIRATORY DISTRESS SYNDROME, STROKE AND ULCER | ELI LILLY AND COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0882706-A1 | Cell adhesion inhibitors | ELI LILLY AND COMPANY (US) | 1998-12-09 | — | — | EP | disclosed |