Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | LMNA | P02545 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | HTT | P42858 | 6/20 | 0.45 |
| ▸ | MITF | O75030 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102117 | 0.91 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTHTTMITF | |
| SCHEMBL8102608 | 0.89 | PTPN1 (0.46) | ALDH1A1LMNAMAPTHTTMITF | |
| SCHEMBL8092785 | 0.88 | PTPN1 (0.48) | ALDH1A1LMNAMAPTHTTMITF | |
| SCHEMBL8106476 | 0.87 | FGFR1 (0.46) | ALDH1A1LMNAMAPTHTTMITF | |
| SCHEMBL8102167 | 0.84 | DHODH (0.51) | ALDH1A1LMNAMAPTHTTMITF | |
| SCHEMBL8102537 | 0.83 | LMNA (0.44) | ALDH1A1LMNAMAPTHTTMITF | |
| SCHEMBL8100473 | 0.82 | DHODH (0.42) | ALDH1A1LMNAMAPTHTTMITF | |
| SCHEMBL8100744 | 0.81 | MAPT (0.51) | ALDH1A1LMNAMAPTHTTMITF | |
| SCHEMBL8100896 | 0.81 | KMT2A (0.39) | ALDH1A1LMNAMAPTHTTMITF | |
| SCHEMBL8092964 | 0.79 | MAPT (0.46) | ALDH1A1LMNAMAPTHTTMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013674-A | INDENONE AMIDE DERIVATIVES, USEFUL FOR FOR THE INHIBITION OF LEUKOCYTE ADHERENCE TO ENDOTHELIAL CELLS; USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES, AS ARTHRITIS, ASTHAMA, PSORIASIS, RESPIRATORY DISTRESS SYNDROME, STROKE AND ULCER | ELI LILLY AND COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0882706-A1 | Cell adhesion inhibitors | ELI LILLY AND COMPANY (US) | 1998-12-09 | — | — | EP | disclosed |