SCHEMBL8092964

SCHEMBL8092964

O=CNC1=C(CCCCCCl)c2ccccc2C1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.46
NPSR1 Q6W5P4 5/20 0.46
ALDH1A1 P00352 4/20 0.46
CASP3 P42574 3/20 0.46
SENP8 Q96LD8 3/20 0.46
SENP7 Q9BQF6 3/20 0.46
SENP6 Q9GZR1 3/20 0.46
RAB9A P51151 3/20 0.46
LMNA P02545 5/20 0.35
HTT P42858 4/20 0.35
MITF O75030 4/20 0.35
NSD2 O96028 4/20 0.35
KMT2A Q03164 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 3/20 0.35
USP2 O75604 1/20 0.35
POLB P06746 1/20 0.35
CDC25A P30304 7/20 0.35
HSP90AA1 P07900 2/20 0.35
G6PD P11413 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8100744 0.94 MAPT (0.51) MAPTNPSR1ALDH1A1CASP3SENP8
SCHEMBL8092785 0.86 PTPN1 (0.48) MAPTALDH1A1RAB9ALMNAHTT
SCHEMBL8102608 0.84 PTPN1 (0.46) MAPTALDH1A1RAB9ALMNAHTT
SCHEMBL8102117 0.82 ALDH1A1 (0.40) MAPTNPSR1ALDH1A1CASP3SENP8
SCHEMBL8100473 0.80 DHODH (0.42) MAPTNPSR1ALDH1A1CASP3SENP8
SCHEMBL8092901 0.79 ALDH1A1 (0.45) MAPTNPSR1ALDH1A1CASP3SENP8
SCHEMBL8102032 0.78 HSP90AA1 (0.55) MAPTNPSR1ALDH1A1CASP3SENP8
SCHEMBL8102537 0.78 LMNA (0.44) MAPTNPSR1ALDH1A1CASP3SENP8
SCHEMBL8102167 0.77 DHODH (0.51) MAPTNPSR1ALDH1A1CASP3SENP8
SCHEMBL8092562 0.76 MAPT (0.45) MAPTNPSR1ALDH1A1CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6100263-A CONTROLLING ANIMAL PESTS OR HARMFUL FUNGI; 2-METHOXYIMINO-2-(2'-(1?-METHYL,1?-(1?'-(6??-(4??'-CHLOROPHENYL) -HEXYLOXYIMINO) ,2?',2?'-DIMETHYLPROPYL))IMINOOXYMETHYL)-PHENYLACETIC ACID MONOMETHYLAMIDE, FOR EXAMPLE BASF AKTIENGESELLSCHAFT (DE) 2000-08-08 US disclosed
US-6013674-A INDENONE AMIDE DERIVATIVES, USEFUL FOR FOR THE INHIBITION OF LEUKOCYTE ADHERENCE TO ENDOTHELIAL CELLS; USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES, AS ARTHRITIS, ASTHAMA, PSORIASIS, RESPIRATORY DISTRESS SYNDROME, STROKE AND ULCER ELI LILLY AND COMPANY (US) 2000-01-11 US disclosed
US-5990339-A Phenylacetic acid derivatives, and use as fungicides BASF AKTIENGESELLSCHAFT (DE) 1999-11-23 US disclosed
US-5889059-A PESTICIDE OR FUNGICIDE BASF AKTIENGESELLSCHAFT (DE) 1999-03-30 US disclosed
US-5874467-A CONTROLLING ANIMAL PESTS AND HARMFUL FUNGI; TRI-SUBSTITUTED BENZENE RING: ESTER OR CARBOXYLIC ACID, OPTIONALLY C-SUBSTITUTED OXIME GROUPS, AND HALOGENATED ALKYL, CYANO, NITRILE, ALKYL OR ALKOXY GROUPS BAYER HERBERT (DE) 1999-02-23 US disclosed
EP-0882706-A1 Cell adhesion inhibitors ELI LILLY AND COMPANY (US) 1998-12-09 EP disclosed