Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NQO2 | P16083 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 3/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101251 | 1.00 | APP (0.46) | APPPTGS2KDM4EMEN1MAPT | |
| SCHEMBL4713012 | 0.86 | GRM4 (0.49) | PTGS2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4713014 | 0.86 | GRM4 (0.49) | PTGS2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL5788380 | 0.84 | PTGS2 (0.54) | PTGS2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL5788387 | 0.84 | PTGS2 (0.54) | PTGS2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL5789176 | 0.84 | CASP3 (0.46) | KDM4EMEN1MAPTKMT2ACYP1A1 | |
| SCHEMBL5789179 | 0.84 | CASP3 (0.46) | KDM4EMEN1MAPTKMT2ACYP1A1 | |
| SCHEMBL5786303 | 0.84 | APP (0.53) | APPMEN1MAPTKMT2ANQO2 | |
| SCHEMBL5786300 | 0.84 | APP (0.53) | APPMEN1MAPTKMT2ANQO2 | |
| SCHEMBL5787722 | 0.83 | P4HB (0.38) | KDM4EMAPTCA12CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000159751-A | BENZENE DERIVATIVE | TORII YAKUHIN KK | 2000-06-13 | — | — | JP | disclosed |