SCHEMBL810147

SCHEMBL810147

C=Cc1cc(CCl)ccc1C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
TTR P02766 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809404 0.84 KDM4E (0.36) KDM4ECYP3A4CYP2C19HIF1ATTR
SCHEMBL29467223 0.84 KDM4E (0.36) KDM4ECYP3A4CYP2C19HIF1ATTR
SCHEMBL11463025 0.82 TRPA1 (0.39) KDM4EALDH1A1
SCHEMBL25554831 0.80 CYP4F2 (0.33) ALDH1A1
SCHEMBL19346369 0.78 ESR1 (0.44) KDM4ECYP3A4CYP2C19HIF1AALDH1A1
SCHEMBL810043 0.78 ALDH1A1 (0.45) TTRALDH1A1
SCHEMBL27520565 0.77 GABRA1 (0.42) KDM4ECYP3A4CYP2C19HIF1ATTR
SCHEMBL810222 0.76 TTR (0.49) KDM4ECYP3A4TTRALDH1A1
SCHEMBL28877208 0.76 SKP2 (0.51) CYP3A4CYP2C19ALDH1A1
SCHEMBL7695106 0.74 HPGD (0.46) KDM4EHIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012015977-A3 HIGHLY PORTABLE AND STABLE WORK STATION HERSCHLER MATTHEW B (US) 2012-05-10 WO disclosed
EP-2192645-B1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORP (JP) 2011-11-30 EP disclosed
US-20110250525-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORPORATION (JP) 2011-10-13 US disclosed
EP-2192645-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME Tokuyama Corporation (JP) 2010-06-02 EP disclosed