Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029746 | 0.89 | GLO1 (0.41) | GLO1KDM4ETDP1LMNAHTT | |
| SCHEMBL6635871 | 0.83 | BRPF1 (0.48) | ARLMNAHTTNPC1GAA | |
| SCHEMBL6635525 | 0.83 | AR (0.48) | ARLMNAHTTGAAKMT2A | |
| SCHEMBL8026525 | 0.82 | ALDH1A1 (0.41) | GLO1KDM4ETSHRKMT2ASLC40A1 | |
| SCHEMBL8028284 | 0.82 | GLO1 (0.40) | GLO1KDM4EGAATSHRKMT2A | |
| SCHEMBL8026444 | 0.78 | GLO1 (0.46) | GLO1TDP1SLC40A1 | |
| SCHEMBL8026558 | 0.77 | GLO1 (0.48) | GLO1TDP1SLC40A1STAT3BRPF1 | |
| SCHEMBL8017545 | 0.74 | F2 (0.48) | GLO1TDP1LMNAKMT2ASLC40A1 | |
| SCHEMBL6642117 | 0.73 | F2 (0.47) | HTTNPC1GAAKMT2AALDH1A1 | |
| SCHEMBL8029744 | 0.73 | F2 (0.60) | LMNABRPF1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121308-A | INDOLE AND BENZIMIDAZOLE ANTITHROMBOTIC COMPOUNDS, SUCH AS 1-METHYL-2-(N-(4-AMIDINOPHENYL)-AMINOMETHYL)-5-(N-(HYDROXYCARBONYLMETHYL) -QUINOLINE-8-SULPHONYLAMINO)-INDOLE | BOEHRINGER INGELHEIM KG (DE) | 2000-09-19 | — | — | US | disclosed |