SCHEMBL8101809

SCHEMBL8101809

Cc1c(C(F)(F)F)[nH]c(=O)n(-c2c(F)cc(Cl)c3ocnc23)c1=O

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 1/20 0.30
CCND1 P24385 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4782020 0.76 USP2 (0.36) CDK4CCND1
SCHEMBL8102067 0.74 GRIN2D (0.31) CDK4CCND1
SCHEMBL7822671 0.72 GRIN2D (0.37) CDK4CCND1
SCHEMBL8336393 0.72 CDK4 (0.33) CDK4CCND1
SCHEMBL22495466 0.67 HTT (0.40)
SCHEMBL9384318 0.67 MAOA (0.34) CDK4CCND1
SCHEMBL9387652 0.65 PPOX (0.45)
SCHEMBL6683932 0.65
SCHEMBL22467858 0.64 BCAT1 (0.42)
SCHEMBL7162422 0.64 BCAT1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1047693-A1 HERBICIDES 3-(BENZAZOL-4-YL)PYRIMIDINE-DIONE-DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2000-11-02 EP disclosed
WO-1999031091-A1 HERBICIDES 3-(BENZAZOL-4-YL)PYRIMIDINE-DIONE-DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1999-06-24 WO disclosed