Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 11/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 11/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 11/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 11/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 11/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 11/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782020 | 0.73 | USP2 (0.36) | TSHRCDK4CCND1 | |
| SCHEMBL8101809 | 0.72 | CDK4 (0.30) | CDK4CCND1 | |
| SCHEMBL6971078 | 0.71 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL8336393 | 0.69 | CDK4 (0.33) | CDK4CCND1HTT | |
| SCHEMBL22495466 | 0.69 | HTT (0.40) | HTT | |
| SCHEMBL22467858 | 0.65 | BCAT1 (0.42) | ALDH1A1TSHRHTT | |
| SCHEMBL9387652 | 0.65 | PPOX (0.45) | — | |
| SCHEMBL6980225 | 0.65 | PPOX (0.42) | — | |
| SCHEMBL9384318 | 0.64 | MAOA (0.34) | CDK4CCND1 | |
| SCHEMBL8612005 | 0.64 | TP53 (0.34) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131319-A2 | 3- BENZ(OX/THI)AZOL-7-YL -1H-PYRIMIDINE-2,4-DIONES | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000028822-A2 | HERBICIDAL 3-(BENZO(OX/THI)AZOL-7-YL)-1H-PYRIMIDINE-2,4-DIONES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-25 | — | — | WO | disclosed |