Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654256 | 0.90 | ALDH1A1 (0.47) | ALDH1A1LMNAF2PRSS1PRSS2 | |
| SCHEMBL6117427 | 0.82 | SMN1; SMN2 (0.54) | ALDH1A1LMNAPOLBTSHRMAPK1 | |
| SCHEMBL6112832 | 0.81 | PTGS2 (0.52) | ALDH1A1LMNAPOLBTSHRMAPK1 | |
| SCHEMBL7465466 | 0.81 | POLB (0.59) | LMNAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL5186820 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LMNAPOLBTSHRMAPK1 | |
| SCHEMBL6118551 | 0.79 | L3MBTL1 (0.47) | ALDH1A1LMNAF2PRSS1PRSS2 | |
| SCHEMBL6118827 | 0.79 | MAPT (0.52) | ALDH1A1LMNAPOLBTSHRMAPK1 | |
| SCHEMBL5653136 | 0.78 | ALDH1A1 (0.45) | ALDH1A1LMNAPOLBCYP3A4HPGD | |
| SCHEMBL5653135 | 0.78 | SMN1; SMN2 (0.51) | ALDH1A1LMNAF2PRSS1PRSS2 | |
| SCHEMBL741260 | 0.76 | MAPK1 (0.58) | ALDH1A1LMNAF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054029-A1 | Method of improving stability of aromatic polycarbodimides | ROHM AND HAAS COMPANY (US) | 2000-11-22 | — | — | EP | disclosed |
| US-5045226-A | Reaction product of tin compound with sulfonyl isocyanate, storage stability, polyurethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |
| US-4824595-A | Polyisocyanate compositions containing reversibly blocked catalysts and addition products of sulfonyl isocyanates with catalysts having a tin(II)- or tin(IV)-carboxylate structure | BAYER AKTIENGESELLSCHAFT (DE) | 1989-04-25 | — | — | US | disclosed |
| EP-0172379-B1 | MATERIAL FOR ORTHOPAEDIC BANDAGES | BAYER AG (DE) | 1989-04-19 | — | — | EP | disclosed |
| EP-0232541-A2 | Polyisocyanate compositions containing latent tin-catalysts, their use in the preparation of polyurethane resins and reaction products of sulfonyl isocyanates with selected tin compounds | BAYER AG (DE) | 1987-08-19 | — | — | EP | disclosed |
| US-4638795-A | FOR MEDICAL AND VETERINARY USE; BASED ON POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-01-27 | — | — | US | disclosed |
| US-4614785-A | TERTIARY PHOSPHINE OR PERALKYLATED PHOSPHORUS ACID TRIAMIDE CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | disclosed |
| EP-0173252-A2 | Process for the preparation of oligomeric polyisocyanates and their use in the preparation of polyurethane plastics | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0172379-A1 | Material for orthopaedic bandages | BAYER AG (DE) | 1986-02-26 | — | — | EP | disclosed |
| EP-0132675-A2 | Preparations of polyisocynate containing reversibly blocked catalysts, process for their production, their use in the production of polyurethanes, and addition products of sulfonylisocyanates on catalysts with a structure of carboxylates of tin II or IV | BAYER AG (DE) | 1985-02-13 | — | — | EP | disclosed |