Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.46 |
| ▸ | ABL1 | P00519 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
| ▸ | BCR | P11274 | 3/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794439 | 0.84 | ALOX5 (0.50) | ESR1ESR2MEN1KMT2AALOX5 | |
| SCHEMBL3990520 | 0.82 | ALOX5 (0.46) | ESR1ESR2MEN1KMT2AALOX5 | |
| SCHEMBL6824955 | 0.78 | HSD17B1 (0.58) | ESR1ESR2HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL27606388 | 0.78 | ESR2 (0.47) | ESR1ESR2MEN1KMT2AALOX5 | |
| SCHEMBL9004859 | 0.78 | ESR1 (0.46) | ESR1ESR2MEN1KMT2AALOX5 | |
| SCHEMBL6373456 | 0.77 | ALOX5 (0.50) | ESR1ESR2ALOX5 | |
| SCHEMBL9536490 | 0.75 | ESR1 (0.57) | ESR1ESR2ALOX5HSD17B1HSD17B2 | |
| SCHEMBL27606371 | 0.74 | ESR1 (0.42) | ESR1ESR2MEN1KMT2AALOX5 | |
| SCHEMBL2341383 | 0.74 | MMP3 (0.56) | ESR1ESR2MEN1KMT2AALOX5 | |
| SCHEMBL6860834 | 0.72 | ACHE (0.46) | ESR1ESR2MEN1KMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9075058-B2 | Coelenterazine analogues and coelenteramide analogues | JNC CORPORATION (JP) | 2015-07-07 | — | — | US | disclosed |
| US-6133190-A | SUPPORTED MERCAPTOAKYL-SUBSTITUTED POLYSTYRENESULFONATE IS USED AS A CATALYST FOR CONDENSATION OF ALDEHYDE OR KETONE WITH PHENOL TO FORM DIHYDROXY COMPOUND | THE DOW CHEMICAL COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| US-6051658-A | A POLYSTYRENE HAVING MERCAPTOSULFONIC ACID RESIDUE, USEFUL AS CATALYST | THE DOW CHEMICAL COMPANY (US) | 2000-04-18 | — | — | US | disclosed |
| US-5939494-A | CATALYST USEFUL FOR THE CONDENSATION OF AN ALDEHYDE OR KETONE STARTING MATERIAL WITH A PHENOL IS AN INSOLUBLE MERCAPTOSULFONIC ACID COMPOUND | THE DOW CHEMICAL COMPANY (US) | 1999-08-17 | — | — | US | disclosed |
| US-5463140-A | Condensing aldehyde or ketone with phenol in presence of soluble or insoluble mercaptosulfonic acid compound to form geminal bisphenol moiety at each aldehyde or ketone moiety | THE DOW CHEMICAL COMPANY (US) | 1995-10-31 | — | — | US | disclosed |