Sugi Predict

Sugi Predict / Compounds / SCHEMBL810236

SCHEMBL810236

SCHEMBL810236

CC(=O)c1ccc2ccc3cccnc3c2n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.57
▸ KDM4E B2RXH2 4/20 0.57
▸ CCR1 P32246 3/20 0.57
▸ CCR5 P51681 3/20 0.57
▸ CCR8 P51685 3/20 0.57
▸ TDP1 Q9NUW8 3/20 0.57
▸ MMP2 P08253 3/20 0.57
▸ MAPT P10636 2/20 0.57
▸ HTT P42858 2/20 0.57
▸ SMN1; SMN2 Q16637 2/20 0.57
▸ TSHR P16473 2/20 0.57
▸ GMNN O75496 1/20 0.57
▸ TP53 P04637 1/20 0.57
▸ HSP90AA1 P07900 1/20 0.57
▸ CYP3A4 P08684 1/20 0.57
▸ CYP2D6 P10635 1/20 0.57
▸ MMP9 P14780 1/20 0.57
▸ ALOX15 P16050 1/20 0.57
▸ NFKB1 P19838 1/20 0.57
▸ MMP8 P22894 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28782932 0.98 LMNA (0.55) LMNAKDM4ECCR1CCR5CCR8
Phenanthroline SCHEMBL28097109 0.85 LMNA (0.73) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL3930639 0.84 KDM4E (0.66) LMNAKDM4ECCR1CCR5CCR8
Phenanthroline SCHEMBL4881417 0.83 LMNA (0.70) LMNAKDM4ECCR1CCR5CCR8
Phenanthroline SCHEMBL22401704 0.83 LMNA (0.70) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL12548430 0.82 PIM1 (0.62) LMNAKDM4ECCR1CCR5CCR8
Ammonia Solution, Strong SCHEMBL31590844 0.82 KDM4E (0.64) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL4765306 0.82 LMNA (0.57) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL15301396 0.81 KDM4E (0.52) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL30578144 0.81 KDM4E (0.52) LMNAKDM4ECCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114940677-B Method for continuous flow synthesis of 1- (1, 10-phenanthroline-2-yl) ethanone 爱斯特（成都）生物制药股份有限公司 2024-12-24 — — CN claimed
CN-117447467-A Preparation method of 2-acetyl-1, 10-phenanthroline 上海再启生物技术有限公司 2024-01-26 — — CN claimed
CN-117209493-A Preparation method of 2-acetyl-1, 10-phenanthroline 爱斯特（成都）生物制药股份有限公司 2023-12-12 — — CN claimed
CN-114940677-A Method for continuous flow synthesis of 1- (1, 10-phenanthroline-2-yl) ethanone 爱斯特（成都）生物制药股份有限公司 2022-08-26 — — CN claimed
CN-112939969-B Preparation method of 2-acetyl-1, 10-phenanthroline 台州市生物医化产业研究院有限公司 2022-04-19 — — CN claimed
CN-112961154-B Preparation method of 2-acetyl-1, 10-phenanthroline 台州市生物医化产业研究院有限公司 2022-01-28 — — CN claimed
CN-112961154-A Preparation method of 2-acetyl-1, 10-phenanthroline 台州市生物医化产业研究院有限公司 2021-06-15 — — CN claimed
CN-112939969-A Preparation method of 2-acetyl-1, 10-phenanthroline 台州市生物医化产业研究院有限公司 2021-06-11 — — CN claimed
CN-110003203-B Method for synthesizing 2-acetyl-1, 10-phenanthroline 北京燕联化工技术有限公司 2020-07-03 — — CN claimed
CN-102485733-B Preparation of acetyl-substituted-1,10-phenanthroline complex and application of prepared complex as catalyst CHINA PETROLEUM & CHEMICAL 2015-01-14 — — CN claimed
CN-103804428-A Preparation method and application of complex CHINA PETROLEUM & CHEMICAL 2014-05-21 — — CN claimed
CN-101357931-A Imino-1,10-phenanthroline chromium dichloride complex, preparation method and application thereof CHINESE ACAD INST CHEMISTRY (CN) 2009-02-04 — — CN claimed
CN-122011047-A Iron complex, preparation method and application thereof, ethylene oligomerization catalyst and ethylene oligomerization method 中国石油化工股份有限公司 2026-05-12 — — CN disclosed
CN-122011046-A Iron complex, preparation method and application thereof, ethylene oligomerization catalyst and ethylene oligomerization method 中国石油化工股份有限公司 2026-05-12 — — CN disclosed
CN-122011048-A Iron complex, preparation method and application thereof, ethylene oligomerization catalyst and ethylene oligomerization method 中国石油化工股份有限公司 2026-05-12 — — CN disclosed
CN-122011049-A Iron complex, preparation method and application thereof, ethylene oligomerization catalyst and ethylene oligomerization method 中国石油化工股份有限公司 2026-05-12 — — CN disclosed
CN-101357931-A Imino-1,10-phenanthroline chromium dichloride complex, preparation method and application thereof CHINESE ACAD INST CHEMISTRY (CN) 2009-02-04 — — CN disclosed
US-7393971-B2 Method for producing 3,3-dimethyl-2-(1-propenyl) cyclopropanecarboxylate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-07-01 — — US disclosed
US-20070078278-A1 Method for producing 3, 3-dimethyl-2-(1-propenyl) cyclopropanecarboxylate SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2007-04-05 — — US disclosed
EP-1681282-A1 METHOD FOR PRODUCING 3,3-DIMETHYL-2-(1-PROPENYL) CYCLOPROPANE CARBOXYLATE Sumitomo Chemical Company, Limited (JP) 2006-07-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078278-A1 Method for producing 3, 3-dimethyl-2-(1-propenyl) cyclopropanecarboxylate AOC3, PDXK, AIPL1 LMNA 2611/4885KDM4E 1080/4885CCR1 403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.