Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | CCR5 | P51681 | 3/20 | 0.55 |
| ▸ | CCR8 | P51685 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540800 | 0.85 | CCR1 (0.50) | CCR1CCR5PDE10A | |
| SCHEMBL253273 | 0.83 | LMNA (0.55) | CCR1LMNACCR5CCR8KDM4E | |
| SCHEMBL29955429 | 0.81 | ALDH1A1 (0.56) | CCR1LMNACCR5CCR8KDM4E | |
| SCHEMBL6886445 | 0.80 | CCR1 (0.52) | CCR1LMNACCR5CCR8KDM4E | |
| SCHEMBL12548380 | 0.77 | CCR1 (0.61) | CCR1LMNACCR5CCR8KDM4E | |
| SCHEMBL7555954 | 0.77 | CCR1 (0.69) | CCR1LMNACCR5CCR8KDM4E | |
| SCHEMBL10012244 | 0.77 | CCR1 (0.61) | CCR1LMNACCR5CCR8KDM4E | |
| SCHEMBL30331100 | 0.77 | CCR1 (0.61) | CCR1LMNACCR5CCR8KDM4E | |
| SCHEMBL12981757 | 0.77 | CCR1 (0.61) | CCR1LMNACCR5CCR8KDM4E | |
| Phenanthroline SCHEMBL28027444 | 0.75 | LMNA (0.73) | CCR1LMNACCR5CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012030549-A3 | CLEANING APPARATUS FOR FOOD PROCESSING EQUIPMENT | HUSSMANN CORPORATION (US) | 2012-05-10 | — | — | WO | disclosed |
| EP-2222722-B1 | PHENANTROLINE-COMPRISING COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2011-11-30 | — | — | EP | disclosed |
| US-20100267910-A1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION COMPRISING PHENANTHROLINE-COMPRISING IRON COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2010-10-21 | — | — | US | disclosed |
| US-20100234548-A1 | PHENANTHROLINE-COMPRISING COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2010-09-16 | — | — | US | disclosed |
| EP-2222724-A1 | CATALYST SYTEM FOR OLEFIN POLYMERIZATION COMPRISING PHENANTROLINE-COMPRISING IRON COMPLEXES | Basell Polyolefine GmbH (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-2222722-A1 | PHENANTROLINE-COMPRISING COMPLEXES | Basell Polyolefine GmbH (DE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009080236-A1 | PHENANTROLINE-COMPRISING COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080237-A1 | CATALYST SYTEM FOR OLEFIN POLYMERIZATION COMPRISING PHENANTROLINE-COMPRISING IRON COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234548-A1 | PHENANTHROLINE-COMPRISING COMPLEXES | WASF2, BPTF, PICALM | CCR1 2902/4885LMNA 3350/4885CCR5 1887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.