Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684699 | 0.91 | SMN1; SMN2 (0.39) | TAS1R3TAS1R1TAS1R2LMNATP53 | |
| SCHEMBL8111792 | 0.87 | LMNA (0.34) | TAS1R3TAS1R1TAS1R2LMNATP53 | |
| SCHEMBL8111565 | 0.83 | RAB9A (0.36) | TP53NPSR1HTTTDP1SMN1; SMN2 | |
| SCHEMBL9570618 | 0.83 | TP53 (0.35) | TP53NPSR1HTTTDP1SMN1; SMN2 | |
| SCHEMBL5501281 | 0.80 | TSHR (0.35) | LMNANPSR1HTTSMN1; SMN2HPGD | |
| SCHEMBL9501097 | 0.78 | NR1H2 (0.38) | TP53NPSR1HTTTDP1SMN1; SMN2 | |
| SCHEMBL7506823 | 0.78 | MAPT (0.33) | LMNANPSR1HTTTDP1PKM | |
| SCHEMBL15010908 | 0.74 | CES2 (0.51) | SMN1; SMN2HPGDRAB9AGAANPC1 | |
| SCHEMBL18134165 | 0.73 | HSD17B2 (0.38) | LMNASMN1; SMN2HPGDGAAALDH1A1 | |
| SCHEMBL332051 | 0.73 | TP53 (0.37) | TAS1R3TAS1R1TAS1R2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565132-B1 | Benzoheterocyclic compounds | OTSUKA PHARMA CO LTD (JP) | 2000-10-25 | — | — | EP | disclosed |
| EP-0823413-A2 | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |
| US-5591744-A | 1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLATE DERIVATIVES; MICROBIOCIDES | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0287951-B1 | 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents | OTSUKA PHARMA CO LTD (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5495020-A | CHEMICAL INTERMEDIATE FOR BACTERICIDES, MICROBIOCIDES, DISINFECTANTS; SIDE EFFECT REDUCTION, ABSORPTION | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0565132-A2 | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-13 | — | — | EP | disclosed |
| EP-0319906-A2 | Novel quinoline derivatives, processes for preparation thereof and antibacterial agent containing them | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-14 | — | — | EP | disclosed |