Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684699 | 0.88 | SMN1; SMN2 (0.39) | TP53NPSR1HTTTDP1SMN1; SMN2 | |
| SCHEMBL8102404 | 0.83 | TAS1R3 (0.38) | TP53NPSR1HTTTDP1SMN1; SMN2 | |
| SCHEMBL8111565 | 0.80 | RAB9A (0.36) | TP53NPSR1HTTTDP1SMN1; SMN2 | |
| SCHEMBL9501097 | 0.75 | NR1H2 (0.38) | TP53NPSR1HTTTDP1SMN1; SMN2 | |
| SCHEMBL7506823 | 0.75 | MAPT (0.33) | NPSR1HTTTDP1PKMRAB9A | |
| SCHEMBL27407281 | 0.75 | TP53 (0.35) | TP53NPSR1HTTTDP1SMN1; SMN2 | |
| SCHEMBL9135625 | 0.74 | CES2 (0.30) | — | |
| SCHEMBL332051 | 0.74 | TP53 (0.37) | TP53NPSR1HTTTDP1SMN1; SMN2 | |
| SCHEMBL17165495 | 0.72 | SMN1; SMN2 (0.48) | TP53NPSR1HTTTDP1SMN1; SMN2 | |
| SCHEMBL10351474 | 0.72 | HTT (0.34) | NPSR1HTTALDH1A1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550903-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1993-07-14 | — | — | EP | disclosed |
| CN-1068115-A | 7-iso-dihydro-indole-group-quinolone and-1,4 dihydros-1,8 naphthyridine-4-keto carboxylic acid derivatives | BAYER AG (DE) | 1993-01-20 | — | — | CN | disclosed |
| EP-0520240-A1 | 7-Isoindolinyl-quinolone and naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |