Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089150 | 0.89 | HTR2A (0.55) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL8088925 | 0.89 | HTR2A (0.55) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL8097222 | 0.89 | MTNR1A (0.50) | MTNR1AMTNR1BHPGDSCN3A | |
| SCHEMBL8097843 | 0.89 | CNR2 (0.48) | MTNR1AMTNR1B | |
| SCHEMBL8104774 | 0.89 | CNR2 (0.48) | MTNR1AMTNR1B | |
| SCHEMBL8104776 | 0.89 | CNR2 (0.48) | MTNR1AMTNR1B | |
| SCHEMBL8097840 | 0.89 | CNR2 (0.48) | MTNR1AMTNR1B | |
| SCHEMBL8089396 | 0.88 | MTNR1A (0.45) | MTNR1AMTNR1BHPGDHTR2AHTR2C | |
| SCHEMBL8088837 | 0.88 | FFAR1 (0.55) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL8088838 | 0.88 | FFAR1 (0.55) | MTNR1AMTNR1BHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747346-B1 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL MYERS SQUIBB CO (US) | 2000-02-16 | — | — | EP | claimed |