Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696908 | 0.90 | KMT2A (0.44) | KMT2AMEN1ATMSMN1; SMN2CYP1A2 | |
| SCHEMBL1268683 | 0.90 | LDHA (0.47) | MAPTKMT2AMEN1RAB9ALDHA | |
| SCHEMBL532894 | 0.79 | NPC1 (0.57) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL533375 | 0.79 | NPC1 (0.57) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL6924446 | 0.78 | RAB9A (0.46) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL57245 | 0.72 | KMT2A (0.50) | KMT2AMEN1RAB9AATMSMN1; SMN2 | |
| SCHEMBL57101 | 0.72 | MEN1 (0.50) | MAPTKMT2AMEN1RAB9ALDHA | |
| SCHEMBL6565732 | 0.72 | HSD17B10 (0.47) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL805908 | 0.72 | MAPT (0.58) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL6564201 | 0.72 | ELANE (0.52) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |