Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 15/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468021 | 0.91 | CHRM2 (0.39) | CHRM2SCN8A | |
| SCHEMBL8103450 | 0.91 | CHRM2 (0.42) | CHRM2SCN8A | |
| SCHEMBL7467923 | 0.89 | CHRM2 (0.44) | CHRM2SCN8A | |
| SCHEMBL7473528 | 0.88 | CHRM2 (0.35) | CHRM2SCN8A | |
| SCHEMBL8109283 | 0.76 | MEN1 (0.31) | — | |
| SCHEMBL8107605 | 0.72 | HRH3 (0.37) | — | |
| SCHEMBL9777419 | 0.70 | CHRM2 (0.68) | CHRM2SCN8ATMEM97SIGMAR1 | |
| SCHEMBL8103219 | 0.69 | ADORA3 (0.39) | — | |
| SCHEMBL8093773 | 0.69 | CHRM2 (0.33) | CHRM2SCN8A | |
| SCHEMBL7468232 | 0.66 | ADRA2A (0.33) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127369-A | 5,10-dihydrodipyrido[2,3-b:2,3-e]pyrazin and 5,10-dihydrodipyrido[2,3-b:3,2-e]pyrazin compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | claimed |