Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184811 | 0.84 | CYP4F2 (0.38) | TDP1APOBEC3GCYP4F2CYP4A11CA2 | |
| SCHEMBL8698489 | 0.84 | TAAR1 (0.35) | APOBEC3GFOLH1TAAR1HSPA5AKR1B1 | |
| SCHEMBL29534868 | 0.81 | TDP1 (0.55) | TDP1APOBEC3GPTPN1FFAR1TAAR1 | |
| SCHEMBL31203 | 0.81 | TDP1 (0.55) | TDP1APOBEC3GPTPN1FFAR1TAAR1 | |
| SCHEMBL1438428 | 0.79 | — | — | |
| SCHEMBL16236326 | 0.76 | SLC6A2 (0.34) | APOBEC3G | |
| SCHEMBL3022571 | 0.75 | GABRA1 (0.48) | TDP1PTPN1FFAR1ALDH1A1MAPT | |
| SCHEMBL6829700 | 0.75 | ALDH1A1 (0.34) | APOBEC3GTAAR1ALDH1A1TSHRMAPK1 | |
| SCHEMBL98102 | 0.75 | TAAR1 (0.56) | TAAR1CYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL186669 | 0.75 | GABRA1 (0.37) | HPGDKDM4EALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009023669-A1 | SUBSTITUTED 5,6,7,8-TETRAHYDROQUINOLINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE THEREOF | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-02-19 | — | — | WO | claimed |
| US-20090048295-A1 | SUBSTITUTED 5,6,7,8-TETRAHYDROQUINOLINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE THEREOF | JANSSEN PHARMACEUTICE N.V. (BE) | 2009-02-19 | — | — | US | claimed |
| US-4622169-A | ANTHRAQUINONE OR NAPHTHAQUINONE SUBSTITUTED WITH AMINO GROUP REACTED WITH METAL SALT | THE DOW CHEMICAL COMPANY (US) | 1986-11-11 | — | — | US | claimed |
| US-10370536-B2 | Resin composition, prepreg, resin sheet, metal foil-clad laminate, and printed wiring board | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2019-08-06 | — | — | US | disclosed |
| EP-3115418-B1 | RESIN COMPOSITION, PREPREG, RESIN SHEET, METAL-FOIL-CLAD LAMINATED PLATE, AND PRINTED WIRING BOARD | MITSUBISHI GAS CHEMICAL CO (JP) | 2018-05-23 | — | — | EP | disclosed |
| US-20170158854-A1 | RESIN COMPOSITION, PREPREG, RESIN SHEET, METAL-FOIL-CLAD LAMINATED PLATE, AND PRINTED WIRING BOARD | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-06-08 | — | — | US | disclosed |
| EP-3115418-A1 | RESIN COMPOSITION, PREPREG, RESIN SHEET, METAL-FOIL-CLAD LAMINATED PLATE, AND PRINTED WIRING BOARD | Mitsubishi Gas Chemical Company, Inc. (JP) | 2017-01-11 | — | — | EP | disclosed |
| EP-1971611-B1 | ANTI-VIRAL COMPOUNDS | ABBOTT LAB (US) | 2012-10-10 | — | — | EP | disclosed |
| EP-1702919-B1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | MSD KK (JP) | 2012-05-30 | — | — | EP | disclosed |
| EP-2345652-A1 | Antiviral compounds | Abbott Laboratories (US) | 2011-07-20 | — | — | EP | disclosed |
| US-7915411-B2 | Anti-viral compounds | ABBOTT LABORATORIES (US) | 2011-03-29 | — | — | US | disclosed |
| EP-1702919-A1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |
| EP-1063252-B1 | FLAME-RETARDANT RESIN, COMPOSITION THEREOF, AND PROCESS FOR PRODUCING THE SAME | OTSUKA KAGAKU KK (JP) | 2005-06-08 | — | — | EP | disclosed |
| US-6797750-B2 | Flame-retardant epoxy resin composition, molded article thereof, and electronic part | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2004-09-28 | — | — | US | disclosed |
| US-6632891-B1 | Obtained by an ester exchange reaction between the flame retardant phosphazene and the polycarbonate or polyester resin | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2003-10-14 | — | — | US | disclosed |
| US-20030114606-A1 | A phosphazene compound or polyphosphazenes; fireproofing | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2003-06-19 | — | — | US | disclosed |
| EP-1273608-A1 | FLAME-RETARDANT EPOXY RESIN COMPOSITION, MOLDED OBJECT THEREOF, AND ELECTRONIC PART | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2003-01-08 | — | — | EP | disclosed |
| EP-1063252-A1 | FLAME-RETARDANT RESIN, COMPOSITION THEREOF, AND PROCESS FOR PRODUCING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5006542-A | Cardiovascular agents | E. R. SQUIBB & SONS, INC. (US) | 1991-04-09 | — | — | US | disclosed |
| US-4622169-A | ANTHRAQUINONE OR NAPHTHAQUINONE SUBSTITUTED WITH AMINO GROUP REACTED WITH METAL SALT | THE DOW CHEMICAL COMPANY (US) | 1986-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048295-A1 | SUBSTITUTED 5,6,7,8-TETRAHYDROQUINOLINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE THEREOF | C3AR1, C5AR1, C5AR2 | TDP1 3195/4885APOBEC3G 2314/4885PTPN1 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.