SCHEMBL6829700

SCHEMBL6829700

[O]c1ccccc1CCCl

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
TSHR P16473 1/20 0.34
TAAR1 Q96RJ0 4/20 0.33
PNMT P11086 1/20 0.31
IDO1 P14902 1/20 0.31
TRPA1 O75762 1/20 0.30
MAPK1 P28482 1/20 0.30
GSK3B P49841 1/20 0.30
HIF1A Q16665 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4712351 0.86 ALDH1A1 (0.38) ALDH1A1TSHRTAAR1
SCHEMBL8698489 0.84 TAAR1 (0.35) ALDH1A1TAAR1APOBEC3G
SCHEMBL4574904 0.81 TAAR1 (0.40) ALDH1A1TSHRTAAR1PNMTIDO1
SCHEMBL7050681 0.79
SCHEMBL98102 0.75 TAAR1 (0.56) TAAR1
SCHEMBL810350 0.75 TDP1 (0.44) ALDH1A1TSHRTAAR1MAPK1HIF1A
SCHEMBL186669 0.75 GABRA1 (0.37) ALDH1A1
SCHEMBL10534341 0.74 TSHR (0.41) ALDH1A1TSHRTAAR1PNMTIDO1
SCHEMBL587835 0.73 SLC6A4 (0.40) ALDH1A1MAPK1APOBEC3G
SCHEMBL5535889 0.73 HTR1A (0.48) ALDH1A1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6746757-B1 Multilayered molding MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-06-08 US disclosed
EP-0852604-B1 A POLYPHENYLENE OXIDE DELIVERY SYSTEM FOR ADHESIVE COMPOSITIONS ARIZONA CHEM (US) 2002-04-10 EP disclosed
US-5910526-A HEATING AND MIXING PREBLEND COMPRISING A POLYPHENYLENE ETHER AND B-BLOCK COMPATIBLE RESIN TOGETHER WITH STYRENIC-CONJUGATED DIENE-STRYRENIC-A-B-A BLOCK POLYMER; HIGHER TEMPERAURE HOT MELT ADHESIVES ARIZONA CHEMICAL COMPANY (US) 1999-06-08 US disclosed
US-5807915-A HEAT RESISTANCE ARIZONA CHEMICAL COMPANY (US) 1998-09-15 US disclosed
EP-0852604-A4 1998-08-26 EP disclosed
US-5789474-A HOT MELT ADHESIVE ARIZONA CHEMICAL COMPANY (US) 1998-08-04 US disclosed
EP-0852604-A1 A POLYPHENYLENE OXIDE DELIVERY SYSTEM FOR ADHESIVE COMPOSITIONS ARIZONA CHEMICAL COMPANY (US) 1998-07-15 EP disclosed
EP-0381056-B1 Method for preparing an impact resistant thermoplastic resin composition MITSUBISHI CHEM CORP (JP) 1997-09-03 EP disclosed
WO-1997011997-A1 A POLYPHENYLENE OXIDE DELIVERY SYSTEM FOR ADHESIVE COMPOSITIONS ARIZONA CHEMICAL COMPANY (US) 1997-04-03 WO disclosed
EP-0520146-B1 Process for preparing a thermoplastic resin composition MITSUBISHI CHEM CORP (JP) 1997-01-15 EP disclosed
US-5026787-A Blends of polyphenylene ether, polyamides, unsaturated compounds MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-06-25 US disclosed
US-5001181-A polyamide blends with dispersed particles of polyphenylene ether which contain dispersed filler particles; strength, flexibility, solvent resistance MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) 1991-03-19 US disclosed
EP-0415344-A1 Resin composition and process for preparing it MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-03-06 EP disclosed
EP-0381056-A2 Impact resistant thermoplastic resin composition MITSUBISHI CHEMICAL CORPORATION (JP) 1990-08-08 EP disclosed
EP-0357065-A2 Resin composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1990-03-07 EP disclosed
EP-0067217-A4 COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER. GEN ELECTRIC (US) 1983-05-16 EP disclosed
EP-0067217-A1 COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER GENERAL ELECTRIC COMPANY (US) 1982-12-22 EP disclosed
US-4365042-A Compositions of polyphenylene oxides with EPDM-silicone rubber GENERAL ELECTRIC COMPANY (US) 1982-12-21 US disclosed
WO-1982002204-A1 COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER GEN ELECTRIC (US) 1982-07-08 WO disclosed
US-4108805-A FIRE RETARDANT ARMSTRONG CORK COMPANY (US) 1978-08-22 US disclosed