SCHEMBL8698489

SCHEMBL8698489

[O]c1ccccc1CCc1ccccc1[O]

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 6/20 0.35
APOBEC3G Q9HC16 1/20 0.35
HSPA5 P11021 1/20 0.33
FOLH1 Q04609 1/20 0.33
AKR1B1 P15121 1/20 0.33
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HTR1A P08908 1/20 0.32
DRD2 P14416 1/20 0.32
GABRA1 P14867 2/20 0.32
GABRB2 P47870 2/20 0.32
DAO P14920 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ADRB2 P07550 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5535889 0.87 HTR1A (0.48) TAAR1NR1H2NR1H3MAPTHTR1A
SCHEMBL98102 0.84 TAAR1 (0.56) TAAR1HTR1A
SCHEMBL186669 0.84 GABRA1 (0.37) MAPTNPSR1L3MBTL1HTR1AGABRA1
SCHEMBL6829700 0.84 ALDH1A1 (0.34) TAAR1APOBEC3GALDH1A1
SCHEMBL810350 0.84 TDP1 (0.44) TAAR1APOBEC3GHSPA5FOLH1AKR1B1
SCHEMBL2186450 0.81 HSPA5 (0.46) APOBEC3GHSPA5AKR1B1MAPTNPSR1
SCHEMBL4712351 0.80 ALDH1A1 (0.38) TAAR1MAPTNPSR1L3MBTL1ALDH1A1
SCHEMBL8792197 0.80 TDP1 (0.36) TAAR1GABRA1GABRB2
SCHEMBL16236326 0.80 SLC6A2 (0.34) APOBEC3G
SCHEMBL186697 0.80 LIPG (0.47) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0448115-B1 Method for producing a polyolefin TOSOH CORP (JP) 1998-01-07 EP claimed
EP-0448115-A2 Method for producing a polyolefin Tosoh Corporation (JP) 1991-09-25 EP claimed
EP-0448115-B1 Method for producing a polyolefin TOSOH CORP (JP) 1998-01-07 EP disclosed
US-5629390-A Method for producing a polyolefin TOSOH CORPORATION (JP) 1997-05-13 US disclosed
EP-0448115-A2 Method for producing a polyolefin Tosoh Corporation (JP) 1991-09-25 EP disclosed