Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 2/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717986 | 0.81 | GAA (0.56) | KCNK3KCNK9SMN1; SMN2LMNAGAA | |
| SCHEMBL31369140 | 0.81 | GAA (0.56) | KCNK3KCNK9SMN1; SMN2LMNAGAA | |
| Benzoyl Chloride SCHEMBL8103514 | 0.80 | LMNA (0.51) | KCNK3KCNK9LMNAGAACNR2 | |
| SCHEMBL2106763 | 0.79 | KCNK3 (0.76) | KCNK3KCNK9SMN1; SMN2LMNAGAA | |
| SCHEMBL24201 | 0.77 | LMNA (0.60) | KCNK3KCNK9SMN1; SMN2LMNAGAA | |
| SCHEMBL746794 | 0.77 | LMNA (0.64) | KCNK3KCNK9SMN1; SMN2LMNAGAA | |
| SCHEMBL11504889 | 0.77 | CES2 (0.54) | SMN1; SMN2RXFP1 | |
| SCHEMBL10619331 | 0.76 | SMN1; SMN2 (0.46) | KCNK3KCNK9SMN1; SMN2LMNAGAA | |
| SCHEMBL15283719 | 0.76 | ALDH1A1 (0.50) | KCNK3KCNK9ATMTDP1L3MBTL1 | |
| SCHEMBL10410294 | 0.75 | ALDH1A1 (0.50) | KCNK3KCNK9SMN1; SMN2GAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |