Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105285 | 0.91 | MAPT (0.37) | SLC6A4SLC6A2SLC6A3MAPTSMN1; SMN2 | |
| SCHEMBL8105610 | 0.90 | CYP1A2 (0.41) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL8103924 | 0.89 | — | — | |
| SCHEMBL8097866 | 0.89 | NOTUM (0.41) | — | |
| SCHEMBL8105911 | 0.87 | KMT2A (0.35) | CASP3MAPTSMN1; SMN2HDAC1HDAC8 | |
| SCHEMBL8098702 | 0.87 | ALDH1A1 (0.38) | CASP3HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL8105889 | 0.86 | CACNA1H (0.35) | ALDH1A1CYP2D6 | |
| SCHEMBL8097595 | 0.84 | KMT2A (0.37) | CASP3SMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL8098695 | 0.83 | MAPT (0.41) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8097540 | 0.82 | POLB (0.36) | CASP3MAPTSMN1; SMN2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |