Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097583 | 0.89 | NPC1 (0.37) | ALDH1A1MAPTALOX5NPC1TP53 | |
| SCHEMBL8097595 | 0.89 | KMT2A (0.37) | ALDH1A1SMN1; SMN2CASP3TSHR | |
| SCHEMBL8105911 | 0.88 | KMT2A (0.35) | POLBALDH1A1MAPTSMN1; SMN2CASP3 | |
| SCHEMBL8102959 | 0.87 | SMN1; SMN2 (0.38) | ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8098702 | 0.87 | ALDH1A1 (0.38) | ALDH1A1HPGDCASP3HDAC8HDAC6 | |
| SCHEMBL8098460 | 0.87 | NTMT1 (0.35) | ALDH1A1MAPTTP53 | |
| SCHEMBL8097453 | 0.87 | LMNA (0.41) | POLBALDH1A1MAPTSMN1; SMN2CASP3 | |
| SCHEMBL8099147 | 0.86 | POLB (0.41) | POLBALDH1A1MAPTNPC1TP53 | |
| SCHEMBL8105978 | 0.86 | TP53 (0.42) | POLBALDH1A1MAPTTP53NPSR1 | |
| SCHEMBL8097382 | 0.86 | FAAH (0.32) | ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |