Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105911 | 0.89 | KMT2A (0.35) | KMT2AATMCASP3SMN1; SMN2HSD17B10 | |
| SCHEMBL8097540 | 0.89 | POLB (0.36) | TSHRCASP3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8097453 | 0.88 | LMNA (0.41) | KMT2AATMCASP3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8102959 | 0.86 | SMN1; SMN2 (0.38) | L3MBTL1SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL8105285 | 0.84 | MAPT (0.37) | KMT2AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8103628 | 0.84 | SLC6A4 (0.37) | KMT2AL3MBTL1CASP3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8105889 | 0.83 | CACNA1H (0.35) | ALDH1A1 | |
| SCHEMBL8098460 | 0.81 | NTMT1 (0.35) | KMT2AALDH1A1 | |
| SCHEMBL8098702 | 0.81 | ALDH1A1 (0.38) | KMT2AMAPK1CASP3HSD17B10ALDH1A1 | |
| SCHEMBL8105610 | 0.81 | CYP1A2 (0.41) | KMT2AHTTSMN1; SMN2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |