Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097595 | 0.89 | KMT2A (0.37) | KMT2ACASP3SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8105889 | 0.89 | CACNA1H (0.35) | ALDH1A1 | |
| SCHEMBL8097540 | 0.88 | POLB (0.36) | TP53POLBCASP3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8103628 | 0.87 | SLC6A4 (0.37) | KMT2ACASP3SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8098702 | 0.87 | ALDH1A1 (0.38) | KMT2ACASP3ALDH1A1HSD17B10HDAC1 | |
| SCHEMBL8097453 | 0.87 | LMNA (0.41) | KMT2ATP53LMNAPOLBCASP3 | |
| SCHEMBL8105610 | 0.87 | CYP1A2 (0.41) | KMT2ALMNAPOLBALOX12SMN1; SMN2 | |
| SCHEMBL8105285 | 0.85 | MAPT (0.37) | KMT2APOLBSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8103924 | 0.85 | — | — | |
| SCHEMBL8098695 | 0.84 | MAPT (0.41) | KMT2ALMNAALDH1A1MAPTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |