Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28415632 | 0.94 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9AMAOAALDH1A1PLAU | |
| SCHEMBL27432910 | 0.92 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9AMAOAALDH1A1PLAU | |
| SCHEMBL28419900 | 0.79 | THRB (0.54) | SMN1; SMN2RAB9AALDH1A1NPC1KMT2A | |
| SCHEMBL8103773 | 0.79 | GAA (0.47) | SMN1; SMN2RAB9AALDH1A1LMNANPC1 | |
| SCHEMBL7121966 | 0.76 | THRB (0.51) | SMN1; SMN2ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL6310745 | 0.76 | CA4 (0.42) | SMN1; SMN2RAB9AALDH1A1NPC1CYP2C19 | |
| SCHEMBL31275045 | 0.76 | LTA4H (0.47) | ALDH1A1PKM | |
| SCHEMBL7306942 | 0.76 | CA1 (0.52) | MAOAALDH1A1PKMHPGD | |
| SCHEMBL28410277 | 0.75 | THRB (0.58) | SMN1; SMN2ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL28674679 | 0.75 | CA4 (0.41) | SMN1; SMN2RAB9AALDH1A1NPC1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121476-A | Process for preparing dithiocarbonimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0811612-B1 | Process for preparing dithiocarbonimide derivatives | SUMITOMO CHEMICAL CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0811612-A1 | Process for preparing dithiocarbonimide derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1997-12-10 | — | — | EP | disclosed |